Study
This research examines BPC 157, a peptide that comes from the stomach, as a potential treatment for side effects caused by NSAIDs (non-steroidal anti-inflammatory drugs). BPC 157 shows benefits in multiple areas where NSAIDs cause problems:
The peptide protects the stomach, intestines, liver, and brain from damage. It helps with joint inflammation and pain management. The compound improves blood vessel function and helps with blood clotting issues. It also assists with wound healing.
BPC 157 works at very low doses, whether taken by mouth or injection. No toxic effects were found even at high doses. The study suggests BPC 157 could serve as a protective agent when people need to take NSAIDs.
Research Methods
The document presents this as a review study, meaning it analyzes existing research rather than conducting new experiments. The researchers examined BPC 157’s effects through multiple angles:
- Clinical trials for inflammatory bowel disease
- Tests of stability in stomach acid
- Safety assessments at various doses
- Comparative studies with NSAIDs
- Evaluation across multiple body systems including digestive tract, liver, brain, and blood vessels
Publication Details
- Title: Toxicity by NSAIDs. Counteraction by stable gastric pentadecapeptide BPC 157
- Researchers: Predrag Sikiric and team
- Publication: Current Pharmaceutical Design
- Publication date: 2013
- PMID: 22950504
- DOI: 10.2174/13816128130111
- Source URL: https://pubmed.ncbi.nlm.nih.gov/22950504/